1. Limbal.ring
2. Limbal Ring Eye

A limbal ring is a dark ring around the iris of the eye, where the sclera meets the cornea. It is a dark-colored manifestation of the corneal limbus resulting from optical properties of the region. The appearance and visibility of the limbal ring can be negatively affected by a variety of medical conditions concerning the peripheral cornea. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The final days of the Ringling Bros. Circus 14 photos. The 'Greatest Show on Earth' may have come to an end, but that doesn't necessarily mean its lions and tigers will be able to retire to a more. The limbal ring certainly makes your right eye look quite a bit bigger, without the limbal ring being as obvious as it would be on lighter coloured eyes. Knotlob, 09:19 AM #3.

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Limbal.ring

Limbal Ring Eye

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Prominent limbal ring

A limbal ring is a dark ring around the iris of the eye, where the sclera meets the cornea.^[1] It is a dark-colored manifestation of the corneal limbus resulting from optical properties of the region.^[2] The appearance and visibility of the limbal ring can be negatively affected by a variety of medical conditions concerning the peripheral cornea.^[3] It has been suggested that limbal ring thickness may correlate with health or youthfulness and may contribute to facial attractiveness.^[3][4] Some contact lenses are colored to simulate limbal rings.^[1]

Youth, health, and attractiveness[edit]

Both health and age are positively correlated with a prominent limbal ring.^[5] For instance, a darker limbal ring tends to be found more attractive than the absence of a limbal ring, suggesting that both sexes 'use the limbal ring as a probabilistic indicator of reproductive fitness'.^[5] Furthermore, limbal rings appear to be most noticeable 'for individuals relatively free from chronic health issues'.^[6]

The limbal ring is thought to contain corneal epithelium stem cells.^[7] Diseases involving a limbal stem cell deficiency are associated with blindness, as those with such deficiencies are 'unable to maintain a stable corneal surface.'.^[8] Transplantation of limbal stem cells is a promising therapy for limbal stem cell deficiency.^[9]

See also[edit]

References[edit]

1. ^ ^abJohnson and Johnson Vision Care Inc. Tinted contact lenses with combined limbal ring and iris patterns. US7246903B2. United States Patent and Trademark Office, July 24, 2007. http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&p=1&u=/netahtml/PTO/srchnum.html&r=1&f=G&l=50&d=PALL&s1=7246903.PN.
2. ^Shyu, Betsy P.; Wyatt, Harry J. (2009). 'Appearance of the Human Eye: Optical Contributions to the 'Limbal Ring''. Optometry and Vision Science. 86 (9): E1069–77. doi:10.1097/OPX.0b013e3181b4f010. PMID19648842.
3. ^ ^abPeshek, Semmaknejad, Hoffman, Foley (2011). 'Preliminary evidence that the limbal ring influences facial attractiveness'(PDF). Evolutionary Psychology. 9 (2): 137–146. doi:10.1177/147470491100900201.CS1 maint: uses authors parameter (link)
4. ^Brown M, Sacco DF (2018). 'Put a (Limbal) Ring on It: Women Perceive Men's Limbal Rings as a Health Cue in Short-Term Mating Domains'. Pers Soc Psychol Bull. 44 (1): 80–91. doi:10.1177/0146167217733072. PMID28978250.
5. ^ ^abPeshek, Semmaknejad, Hoffman, Foley (2011). 'Preliminary evidence that the limbal ring influences facial attractiveness'(PDF). Evolutionary Psychology. 9 (2): 137–146. doi:10.1177/147470491100900201.CS1 maint: uses authors parameter (link)
6. ^Brown M, Sacco DF (2018). 'Put a (Limbal) Ring on It: Women Perceive Men's Limbal Rings as a Health Cue in Short-Term Mating Domains'. Pers Soc Psychol Bull. 44 (1): 80–91. doi:10.1177/0146167217733072. PMID28978250.
7. ^Li, De-Quan; Chen, Zhuo; Song, Xiu Jun; de Paiva, Cintia S.; Kim, Hyun-Seung; Pflugfelder, Stephen C. (April 2005). 'Partial enrichment of a population of human limbal epithelial cells with putative stem cell properties based on collagen type IV adhesiveness'. Experimental Eye Research. 80 (4): 581–590. doi:10.1016/j.exer.2004.11.011. ISSN0014-4835. PMC2906384. PMID15781286.
8. ^James, S. Elizabeth; Rowe, Andrea; Ilari, Luca; Daya, Sheraz; Martin, Robin (July 2001). 'The Potential for Eye Bank Limbal Rings to Generate Cultured Corneal Epithelial Allografts'. Cornea. 20 (5): 488–494. doi:10.1097/00003226-200107000-00010. ISSN0277-3740. PMID11413404.
9. ^Utheim, O. A.; Pasovic, L.; Raeder, S.; Eidet, J. R.; Fostad, I. G.; Sehic, A.; Roald, B.; Paz, M. F. de la; Lyberg, T.; Dartt, D. A.; Utheim, T. P. (2019-03-12). 'Effects of explant size on epithelial outgrowth, thickness, stratification, ultrastructure and phenotype of cultured limbal epithelial cells'. PLOS One. 14 (3): e0212524. Bibcode:2019PLoSO..1412524U. doi:10.1371/journal.pone.0212524. ISSN1932-6203. PMC6413940. PMID30861002.

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